SN Iyer (Lions (-3.5) at 49ers: The Lions are more limping than leaping defensively, but their offense again has adjusted to carry a bigger burden of winning. This current state of the 49ers' offense and defense isn't enough to trust they can outscore them again, massive comeback or not, in a disappointing rematch of last season's NFC championship game. Pick: Lions win 27-24 but fail to cover the spread.): https://www.sportingnews.com/us/nfl/news/nfl-picks-predictions-against-spread-week-17-chiefs-ravens/21479632cb6b31496ff51ae6
SN Bender (Detroit Lions (-3.5) at San Francisco 49ers - The 49ers have been eliminated from playoff contention, so they will be relegated to spoiler mode in this NFC championship rematch. These are two top-10 statistical offenses, and the Lions have injuries on defense, so a shootout could be in the works. Jahmyr Gibbs had 154 total yards in his first game as the lead back for Detroit. He could pop off against a run defense that allows 121 yards per game. Pick: Lions 31, 49ers 24): https://www.sportingnews.com/us/nfl/news/nfl-picks-predictions-week-17-commanders-vikings-packers/49ed8c4e6e44442a54e12551
USA Today (All 6 pick the Lions to win by scores of 34-26, 28-17, 37-27, 28-20, 35-24, 26-16): https://www.usatoday.com/story/sports/nfl-picks/2024/12/24/nfl-week-17-picks-spread-predictions-locks-chiefs-steelers-christmas/77184408007/
CBS Breech (Lions 34-20 over 49ers): https://www.cbssports.com/nfl/news/nfl-week-17-picks-and-score-predictions-chiefs-win-christmas-thriller-over-steelers-bengals-beat-broncos/
CBS Sullivan (Lions at 49ers: It's a shame that this is a dud of a matchup. At the start of the season, this was circled as possibly one of the top head-to-heads of the entire year and possibly an NFC Championship preview. However, the Niners have been run over by a reindeer and have been dealing with injuries wire-to-wire, which now has them mathematically eliminated from the playoffs. Meanwhile, the Lions should have no problem getting up for this game as they need to win out to secure the NFC North and the No. 1 seed in the conference, so we're expecting an all-out effort here. Detroit is a stellar 6-1 ATS on the road this season, which includes a 5-1 ATS record as a road favorite. Pair those trends with San Francisco's pedestrian 4-4 ATS record at home, and this should be pretty lopsided. Projected score: Lions 30, 49ers 20): https://www.cbssports.com/nfl/news/nfl-week-17-odds-picks-chargers-cover-as-road-favorites-vs-patriots-lions-thrash-49ers-in-prime-time/
Walter football (Week 17 NFL Pick: Lions 38, 49ers 27): https://walterfootball.com/nflpicks2024_17late.php
Pro Pick (Detroit (13-2) at San Francisco (6-9) - Line: Lions minus 4. The Lions aim to avenge their loss in the NFC championship game, though this matchup lost its luster because the 49ers are eliminated from the playoff race. Detroit clinches the NFC’s No. 1 seed with a win if the Packers beat the Vikings. If Minnesota beats Green Bay, the Lions have to beat the Vikings in Week 18 to win the division and secure the top seed so the result against San Francisco won’t matter. In that case, Dan Campbell could choose to rest some of his starters in preparation for a winner-take-all regular-season finale. LIONS: 26-23): https://apnews.com/article/mahomes-wilson-stroud-jackson-b3f9d9eb7dbf58622c16cf1caff5d765
NFL.com Video Lions vs 49ers preview | Week 17 (All 10 pick the Lions to win by scores of 33-23, 28-17, 30-20, 30-24, 31-23, 28-14, 34-31, 35-26, 33-22, 30-28): https://www.nfl.com/videos/lions-vs-49ers-preview-week-17
USA Today Lions at 49ers: Predictions, picks, odds for NFL Week 17 game (Both pick the Lions to win by scores of 31-20, 28-20): https://www.usatoday.com/story/sports/nfl/2024/12/25/lions-49ers-picks-predictions-odds-week-17/77182240007/
CBS Dajani (I'll admit, I thought the Lions were going to stumble on the road against the Chicago Bears after the loss to the Bills, in which they lost multiple players due to injury. Instead, Jared Goff, Jahmyr Gibbs and Jameson Williams danced all over Chicago's defense. Six Week 1 starters from the Lions defense are currently on injured reserve. No team has ever been without that many Week 1 defensive starters in a playoff game. However, the Lions don't care. They are going to keep rolling. This week, the Lions get a chance at some NFC Championship revenge against the lowly 49ers. San Francisco has already been eliminated from playoff contention, and is 0-2 in playoff rematches this season. Brock Purdy's offense hasn't scored more than 17 points in two straight weeks, and they are probably ready to turn their attention to 2025. The Lions are the only undefeated team on the road this season, and are an NFL-best 9-1 in prime-time games over the last three years. I'll lay the four points with Detroit. Projected score: Lions 30-23): https://www.cbssports.com/nfl/news/nfl-week-17-picks-odds-spread-best-bets-jayden-daniels-covers-vs-michael-penix-jr-bengals-win-again/
NFL Week 17 game guide: Game projections, playoff breakdowns and what's at stake (Kahler's pick: Lions 40, 49ers 24. Moody's pick: Lions 31, 49ers 24. Walder's pick: Lions 31, 49ers 20): https://www.espn.com/nfl/story/_/page/nflviewguide-43169682/nfl-week-17-picks-schedule-fantasy-football-odds-injuries-stats-2024
MLive (Benjamin Raven’s pick: “Lions 28, 49ers 17: VINDICATION. Let’s see if the Packers give the Lions a belated holiday present by beating the Vikings on Sunday. But I see the Lions getting a win back where last season’s came to a painful finish. Big day for Jahmyr Gibbs ahead.”): https://www.mlive.com/lions/2024/12/lions-49ers-predictions-detroit-eyes-nfc-title-rematch-win-at-levis-stadium.html
Star Tribune Craig (Lions 34, 49ers 20): https://www.startribune.com/nfl-week-17-nfc-north-picks-vikings-packers-lions-bears-mark-craig/601199056
Detroit News (All 4 pick the Lions to win by scores of 31-17, 31-21, 34-24, 31-20): https://www.detroitnews.com/story/sports/nfl/lions/2024/12/28/predictions-detroit-lions-at-san-francisco-49ers/77159280007/
The San Francisco Standard (Lombardi: Lions 31, 49ers 27 - Detroit is an offensive juggernaut. But the Lions are leaking oil defensively and that is the greatest threat to their upcoming Super Bowl bid. Purdy and the 49ers, with their dilapidated O-line, will expose some of those cracks. But the 49ers don’t have enough in the tank to actually win the game. Kawakami: Lions 31, 49ers 13 - Can this really be about Detroit getting some revenge for the NFC Championship Game loss if the Lions have all the motivation (to move closer to clinching the NFC’s No. 1 seed) and the 49ers have nothing to look forward to but the beginning of a long off-season? Well, maybe a little bit. This could get ugly swiftly.): https://sfstandard.com/2024/12/28/49ers-vs-lions-the-standards-5-fast-predictions/
Fox sports Lions vs. 49ers 2024 Prediction, Odds, Picks - Dec 30 (Prediction: Lions 31 - 49ers 18): https://www.foxsports.com/articles/nfl/lions-vs-49ers-2024-prediction-odds-picks-dec-30
SI Lions vs. 49ers Final Score Prediction for Monday Night Football in NFL Week 17 (Final Score Prediction: Lions 30, 49ers 24): https://www.si.com/betting/lions-vs-49ers-final-score-prediction-for-monday-night-football-in-nfl-week-17
Five keys to watch as the Lions face the 49ers; plus injury updates, prediction (PREDICTION: Lions 34, 49ers 24): https://lionslowdown.com/2024/12/30/five-keys-to-watch-as-the-lions-face-the-49ers-plus-injury-updates-prediction/
Freep (All 4 pick the Lions to win by scores of 31-21, 42-17, 33-31, 27-24): https://www.freep.com/story/sports/nfl/lions/2024/12/30/lions-niners-predictions-monday-night-football-nfl-week-17/77291444007/
SI All Lions Predictions: Lions-49ers (All 4 pick the Lions to win by scores of 35-17, 28-20, 37-27, 38-17): https://www.si.com/nfl/lions/news/predictions-lions-49ers-week-seventeen-2024
Lions vs 49ers: Last-minute thoughts and final score prediction (Final score prediction - What could have been an epic playoff preview, a high-stakes rematch of last year’s NFC title game, fizzled away with the Niners’ 6-9 start. Both teams suffered far too many critical injuries. One team adapted, the other wilted. That will be reflected in the scoreboard tonight. Lions 34, 49ers 15): https://lionswire.usatoday.com/2024/12/30/lions-vs-49ers-last-minute-thoughts-game-preview-final-score-prediction/
Sports Book Wire Detroit Lions at San Francisco 49ers odds, picks and predictions (Prediction - Lions 33, 49ers 19): https://sportsbookwire.usatoday.com/2024/12/29/detroit-lions-at-san-francisco-49ers-odds-picks-and-predictions/
Niners Wire Prediction and betting odds for 49ers vs. Lions in Week 17 (49ers vs. Lions prediction, pick:
Prediction: Detroit 30, San Francisco 17): https://ninerswire.usatoday.com/2024/12/30/49ers-vs-lions-odds-picks-predictions-nfl-week-17/
The 49ers’ offensive line and running backs are incredibly banged up. That makes life difficult for San Francisco quarterback Brock Purdy. While the Lions are dealing with their own rash of injuries, Jared Goff and Detroit deliver and exact revenge in a game where they have much more at stake.
Spotskeeda Week 17 MNF Lions vs. 49ers prediction and fantasy picks feat. Jahmyr Gibbs, George Kittle and more (Prediction: Lions 18 - 49ers 15): https://www.sportskeeda.com/nfl/week-17-mnf-lions-vs-49ers-prediction-fantasy-picks-feat-jahmyr-gibbs-george-kittle
Week 17 picks: Bears to snap 9-game skid tonight? Who wins DEN-CIN? (Lions 27-23, Lions 30-21, Lions 31-21, Lions 27-22, 49ers 27-24): https://www.nfl.com/news/week-17-nfl-picks-2024-nfl-season
AZ Central (2 pick the Lions to win by scores of 30-21, 27-17. 1 picks the 49ers to win 26-23): https://www.azcentral.com/story/sports/nfl/2024/12/23/detroit-lions-san-francisco-49ers-picks-predictions-odds-nfl-week-17/77006152007/
CBS Prisco (Detroit Lions (-3.5) at San Francisco 49ers: The 49ers are done, so this rematch of the NFC Championship game from last January means nothing to them. The Lions are playing to win the division. They are playing a second straight road game, which is tough. Look for the 49ers to show some pride here and play well and pull off the upset. Pick: 49ers 30, Lions 29): https://www.cbssports.com/nfl/news/priscos-week-17-nfl-picks-bengals-hold-off-broncos-in-critical-afc-bout-49ers-stun-lions-on-monday-night/
Non-Score Predictions:
FTW (All 6 pick the Lions to win): https://ftw.usatoday.com/2024/12/nfl-straight-up-picks-week-17-steelers-chiefs-bengals-broncos
Athletic (All 6 pick the Lions to win): https://www.nytimes.com/athletic/6020696/2024/12/30/lions-49ers-how-to-watch-odds-picks-betting/
ESPN (10 pick the Lions to win. 1 picks the 49ers to win): https://www.espn.com/nfl/picks
SI (5 pick the Lions to win. 1 picks the 49ers to win): https://www.si.com/nfl/2024-nfl-week-17-staff-expert-picks
CBS (5 pick the Lions to win. 1 picks the 49ers to win): https://www.cbssports.com/nfl/picks/experts/straight-up/17/
PFN (4 pick the Lions to win. 1 picks the 49ers to win): https://www.profootballnetwork.com/nfl-picks-predictions-week-17-2024/
94 Pick the Lions to win. 7 pick the 49ers to win. The Average Predicted Score is (1884-1317/61): Lions 31 49ers 22
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