Packers at Lions (-3, 49 o/u) - The Lions' offense saved the day against the Giants' offense taking it to them through the air with plenty of Jahmyr Gibbs. The Week 1 matchup in Green Bay was rough for Jared Goff, but he should keep feeling it more with Gibbs and Amon St. Brown doing a lot of damage in the short-to-intermediate passing game to take pressure off Goff vs. Micah Parsons. Jordan Love's running game will find a little more tough sledding and has limited firepower with which to match. Pick: Lions win 30-24 and cover the spread.): https://www.sportingnews.com/us/nfl/news/nfl-picks-predictions-against-spread-week-13/d9b75296aacafb37181e638c
SN Bender (Green Bay Packers at Detroit Lions (-2.5) - NFC North rivals meet – and the Packers beat the Lions on Thanksgiving in 2023. Green Bay limited the Lions to 46 rushing yards with three turnovers in Week 1. The Packers are 3-1-1 S/U on the road – but their offense will have to take more chances here. Pick: Lions 28, Packers 20): https://www.sportingnews.com/us/nfl/news/nfl-picks-predictions-week-13/a6f8a9e661bc44556ed32141
CBS Dubin (Prediction: Lions 27, Packers 20): https://www.cbssports.com/nfl/news/packers-vs-lions-where-to-watch-pick-odds-prediction-thanksgiving/
Lions vs. Packers 2025 Prediction, Odds, Picks (Prediction: Lions 26, Packers 21): https://www.foxsports.com/stories/nfl/2025-nfl-week-13-predictions-betting-odds-tv-schedule
Green Bay Packers vs Detroit Lions picks, predictions, odds for NFL Thanksgiving Day game (3 pick the Lions to win by scores of 27-24, 26-23, 24-17): https://www.azcentral.com/story/sports/nfl/2025/11/24/green-bay-packers-detroit-lions-picks-predictions-odds-nfl-week-13/84509193007/
CBS Sullivan (Projected score: Lions 27, Packers 24): https://www.cbssports.com/nfl/news/nfl-week-13-picks-predictions-underdogs-upsets/
NFL Week 13 picks: Upset and score predictions, matchup breakdowns for every game (Lions 27-24, Lions 27-23, Lions 27-24, Lions 26-21, Lions 26-21): https://www.nfl.com/news/nfl-week-13-picks-upset-and-score-predictions-matchup-breakdowns-for-every-game
The Big Lead (Green Bay Packers @ Detroit Lions (-2.5) - The Lions come into this matchup on the outside of the current playoff picture, looking in, just a half game behind the Packers for the #6 spot in the NFC. They managed to come back and beat the Giants last week in a game that many of us expected them to control from the opening gun. As of now, we aren’t really sure if the comeback was a sign of the Lions determination and grit, or it was just a case of a team playing the Giants this season. In fact, I have more questions about teams like the Chargers and Eagles, who didn’t come back and beat New York in the 4th quarter, as every other team that’s played them has. Green Bay took care of business at home last week against a Viking team that seems completely lost, so I’m not sure if we can draw too many conclusions from their performance either. Jordan Love didn’t have to do much of anything for Green Bay to come away with an easy win, but this week should be a completely different story. This is going to be a close game, as the line implies, and I expect both teams to be able to score. Whether or not Josh Jacobs plays, Green Bay will still use the running game to set up any shots downfield by Love. The Lions seem more battle-tested at this point in the season and will be looking to even the score after dropping the week 1 matchup between these two teams. I don’t love the Lions coaching staff in a game that could come down to a key decision late in the game, but I think that’s more of a worry for later if they actually make the postseason. I’ll lean towards the home team to grab this one. Lions 27 – Packers 24): https://www.thebiglead.com/nfl-predicting-the-winner-for-every-game-in-week-13/
Five things to watch as Lions face Packers in key divisional matchup (PREDICTION: Lions 28, Packers 27): https://lionslowdown.com/2025/11/26/five-things-to-watch-as-lions-face-packers-in-key-divisional-matchup/
Pro Picks: Texans will upset the Colts to tighten the race in the AFC South (GREEN BAY (7-3-1) at DETROIT (7-4) - Line: Lions minus 2 1/2. The Packers have won two straight, the defense led by Micah Parsons is dominating and they’re underdogs for the first time this season. The Lions had to rally to beat the lowly Giants after a poor offensive performance in a loss at Philadelphia. They’re looking to avoid getting swept by Green Bay. Detroit is 6-2 in the past eight meetings. The Packers are 20-18 overall and 25-13-1 against the spread as an underdog under coach Matt LaFleur. LIONS: 24-20): https://apnews.com/article/thanksgiving-nfl-stroud-mills-jones-taylor-colts-texans-8b493c5902319a430fef9152864b3ccb
Packers vs. Lions Final Score Prediction for NFL Week 13 (Can Detroit Get Revenge?) (Final Score Prediction: Lions 27, Packers 20): https://www.si.com/betting/packers-vs-lions-final-score-prediction-for-nfl-week-13-can-detroit-get-revenge
Lions vs Packers: Last-minute thoughts and final score prediction (Lions 26, Packers 23): https://lionswire.usatoday.com/story/sports/nfl/lions/2025/11/27/lions-vs-packers-preview-matchup-final-score-prediction/87472514007/
Key Matchups, Predictions for Lions-Packers and More NFL Week 13 Games (Packers (7–3–1) at Lions (7–4) - Key matchup: Jared Goff vs. Jeff Hafley. Key stat: Goff went for just 5.8 yards per attempt in their Week 1 matchup. The Packers know how to beat Jared Goff and the Lions. They’ve already done it. For Detroit, the question is how much to adjust. The Lions were beaten 27–13 with the benefit of a garbage-time touchdown to make the score more respectable. In Week 1, Green Bay hounded Goff, pressuring him 12 times and collecting four sacks while the veteran quarterback posted a -0.9 EPA for the game. Additionally, star running backs Jahmyr Gibbs and David Montgomery were stifled, gaining just 44 yards on 20 carries. The Packers have been tough against the run all season, ranking sixth with -0.10 EPA per rush attempt. Offensive coordinator John Morton must figure out ways to attack Green Bay with 11 games of film to reference. Morton should have a better idea of his own personnel, albeit without tight end Sam LaPorta due to back surgery. In that Week 1 loss, Detroit struggled to handle interior pressures while All-Pro receiver Amon-Ra St. Brown was targeted only six times. For this game to be different, Morton will have to dial up some different runs, schemes to help the guards and center to deal with Micah Parsons when he lines up or stunts inside, and look for St. Brown with LaPorta sidelined. Verdict: Detroit 30, Green Bay 27): https://www.si.com/nfl/key-matchups-predictions-lions-packers-nfl-week-13-games
Laugh at Bill’s Week 13 NFL Predictions, Including Packers-Lions (Prediction: Lions 27, Packers 17): https://www.si.com/nfl/packers/onsi/laugh-at-bills-week-13-nfl-predictions-including-packers-lions
USA Today (5 pick the Lions to win by scores of 27-26, 27-23, 24-20, 28-24, 24-19. 1 picks the Packers to win 27-24): https://www.usatoday.com/story/sports/nfl-picks/2025/11/26/nfl-week-13-picks-spread-predictions-locks-thanksgiving-cowboys-chiefs/87474196007/
Packers vs. Lions preview | Week 13 (7 pick the Lions to win by scores of 30-27, 27-24, 27-24, 22-19, 27-23, 26-23, 24-22. 2 pick the Packers to win by scores of 24-21, 23-20): https://www.nfl.com/videos/packers-vs-lions-preview-week-13
Freep (4 pick the Lions to win by scores of 23-20, 27-24, 28-24, 23-20. 2 pick GB to win by scores of 26-20, 24-23): https://www.freep.com/story/sports/nfl/lions/2025/11/27/detroit-lions-picks-predictions-vs-packers-in-nfl-week-13/87482517007/
MLive.com Lions-Packers Week 13 score predictions from MLive’s beat writers (2 pick the Lions to win by scores of 23-21, 20-17. 1 picks the Packers to win by a score of 35-21): https://www.mlive.com/lions/2025/11/lions-packers-week-13-score-predictions-from-mlives-beat-writers.html
2025 NFL Thanksgiving schedule, picks, odds, injuries (Maldonado's pick: Lions 34, Packers 24. Moody's pick: Lions 30, Packers 27. Walder's pick: Packers 23, Lions 17): https://www.espn.com/nfl/story/_/page/viewersguide47095843/nfl-thanksgiving-picks-schedule-fantasy-football-odds-injuries-stats-2025
PFT’s Week 13 2025 NFL picks: Florio vs. Simms (Packers at Lions (-2.5) - The loser of this game will be getting closer to missing the playoffs. If the Lions lean on Jahmyr Gibbs, they should be able to pull it off. Florio’s pick: Lions 28, Packers 20. Simms’s pick: Packers 24, Lions 23.): https://www.nbcsports.com/nfl/profootballtalk/rumor-mill/news/pfts-week-13-2025-nfl-picks-florio-vs-simms
Packers Wire staff predictions: Week 13 vs. Lions (2 pick the Lions to win by scores of 24-23, 27-20. 2 pick the Packers to win by scores of 27-24, 29-22): https://packerswire.usatoday.com/story/sports/nfl/packers/2025/11/26/packers-wire-staff-predictions-week-13-vs-lions/87480844007/
Packers News (2 pick the Lions to win by scores of 24-21, 35-31. 2 pick the Packers to win by scores of 27-24, 24-21): https://packerswire.usatoday.com/story/sports/nfl/packers/2025/11/26/packers-wire-staff-predictions-week-13-vs-lions/87480844007/
Lions OnSI (3 pick the Packers to win by scores of 27-24, 24-20, 27-24. 1 picks the Lions to win 24-23): https://www.si.com/nfl/lions/onsi/news/expert-predictions-will-detroit-lions-defeat-green-bay-packers
CBS Breech (PICK: Packers 20-17 over Lions | Packers +2.5 | Odds via DraftKings Sportsbook): https://www.cbssports.com/nfl/news/nfl-week-13-picks-score-predictions-cowboys-stun-chiefs-packers-upset-lions-thanksgiving/
Walter football (Week 13 NFL Pick: Packers 24, Lions 23): https://walterfootball.com/nflpicks2025_13early.php
FOX Super 6 Contest: Chris 'The Bear' Fallica's NFL Thanksgiving Picks, Predictions (PREDICTION: Packers 23, Lions 20): https://www.foxsports.com/stories/nfl/fox-super-6-contest-chris-the-bear-fallicas-nfl-thanksgiving-picks-predictions
CBS Dajani (Green Bay Packers at Detroit Lions (-2.5) - Dajani (Packers +2.5): I'm not the biggest Packers fan in the world, but give me the upset! The last time the Packers played in Detroit on Thanksgiving, they upset Jared Goff and Co. Jordan Love is 2-0 on Thanksgiving with five touchdowns and zero interceptions, while Goff is 1-3, averaging 241 passing yards per game and two touchdowns per contest. Believe it or not, this is the Packers' first game as an underdog this season. Obviously the Packers defense is going to have to contain Jahmyr Gibbs and Love is going to have to take care of the football and score some points, but I think Green Bay is more than capable of doing that. Watching Jameis Winston tear up the Lions defense last week was pretty concerning. Prediction: Packers 24, Lions 21.): https://www.cbssports.com/nfl/news/nfl-week-13-picks-dueling-expert-predictions/
CBS Prisco (Green Bay Packers at Detroit Lions (-2.5): The Packers impressed in shutting down the Vikings last week, but this will be a bigger challenge. The Lions offense, especially at home, can be explosive. The Packers offense has not been that. But I think they can get to that in this one against a suspect Lions secondary. Look for a lot of points as the Packers to win it with a late sack to stop a Lions threat. Jordan Love will play big. Pick: Packers 34, Lions 31): https://www.cbssports.com/nfl/news/priscos-week-13-nfl-picks-packers-over-lions-chiefs-top-cowboys/
Non-Score Predictions:
SI (5 pick the Lions. 1 pick the Packers): https://www.si.com/nfl/2025-nfl-week-13-staff-expert-picks
FTW (7 pick the Lions to win. 2 pick the Packers to win): https://ftw.usatoday.com/story/sports/nfl/2025/11/26/nfl-straight-up-picks-week-13-moneyline-packers-lions-texans-colts/87480867007/
ESPN (7 pick the Lions to win. 3 pick the Packers to win): https://www.espn.com/nfl/picks
Athletic (4 pick the Lions. 2 pick the Packers): https://www.nytimes.com/athletic/6835189/2025/11/26/nfl-week-13-picks-chiefs-cowboys-bears-eagles/
66 pick the Lions to win. 28 pick the Packers to win. Average Predicted Score (1660-1549/66): Lions 25 Packers 23