Big lead (LIONS (+9.5) over Bills: Look, it's no secret that the Detroit Lions are our favorite team to bet on and all they do is continue to reward that confidence. Dan Campbell's suddenly-hot unit went out to New Jersey and absolutely dominated a likely playoff team in all three phases of the game. Aidan Hutchinson is looking like a legitimate game-changer. And there's a confidence present that hasn't graced the Motor City since 2014. If this team wasn't called the Lions, a person could convince themselves that they are actually — gulp — good. As for the Bills, it has to be weird to play two games in five days at the same building, one as the home team and one as the road. Sprinkle a little on the moneyline and pray at the altar of Tim "The Tool Man" Taylor. Lions 24, Bills 23): https://www.thebiglead.com/posts/nfl-week-12-predictions-and-picks-against-the-spread-01gjd6116rtr
O'HARA'S WEEK 12 PREVIEW: Lions rolling into Thanksgiving with three-game winning streak (Lions-Bills pick: There is an entirely new atmosphere around the Lions. It comes from winning. No reason to stop now. The Bills are favored by 9.5. My pick: Lions 28, Bills 27.): https://www.detroitlions.com/news/week-12-preview-lions-rolling-into-thanksgiving-with-three-game-winning
Five things to watch as the Lions look to beat the Bills; plus prediction (Prediction: Lions 28, Bills 27) OK, on Sunday I picked the Lions to beat the Giants and got grief for it until afterward. The Bills have the NFL’s second-best offense and their defense allows only 17.4 points per game. Yet, they have lost two of their last three. Numbers aren’t everything – the Lions defense is still ranked 32nd even after shutting down the Giants. After careful deliberation I’m picking the Lions who will be riding an emotional high.): https://lionslowdown.com/2022/11/23/five-things-to-watch-as-the-lions-look-to-beat-the-bills-plus-prediction/
NJ.com (3 pick the Bills to win by scores of 38-17, 38-28, 31-20. 1 picks the Lions to win 30-27): https://www.nj.com/sports/2022/11/nfl-week-12-picks-buffalo-bills-detroit-lions-thanksgiving-predictions.html
SI All Lions (3 pick the Bills to win by scores of 33-24, 31-24, 27-23. 1 picks the Lions to win 31-28): https://www.si.com/nfl/lions/news/predictions-bills-lions
Bills vs. Lions preview | Week 12 (9 pick the Bills to win by scores of 27-17, 30-23, 34-21, 31-22, 45-31, 40-24, 24-21, 31-20, 30-20. 1 picks the Lions to win 24-23): https://www.nfl.com/videos/bills-vs-lions-preview-week-12
SN Iyer (Game of Midweek I: Bills (-9.5, 54 o/u) at Lions: The Bills had some experience adjusting to Ford Field. Although Josh Allen continued to slump, they had to be pleased about getting the traditional running game going and also spreading the ball around more effectively in the passing game. The Lions' young defense has played much better of late and made some big plays, but they struggle to multiple, diverse offenses. Jared Goff hasn't played all that well during the Lions' winning streak and the negative game script will take them out of sticking with the run. Allen has his best game in a month in a complete road rout in a familiar venue. Pick: Bills win 31-20): https://www.sportingnews.com/us/nfl/news/nfl-picks-predictions-against-spread-week-12/ufqbjfktxlzkddiodl1jxpoj
CBS Breech (Buffalo (7-3) at Detroit (4-6): I've seen the movie "Stepbrothers" enough times to know when two people are becoming best friends and definitely seems like the Bills and Lions are becoming best friends. I mean, for one, the Lions were kind enough to let the Bills borrow their house over the weekend. The Lions could have just put their place up on AirBNB, but instead, they let the Bills have it for free and it ended up working out well for everyone involved. And let me just say, I'm glad to see that the Lions set some ground rules. Always set ground rules. These teams likely won't be best friends after this game and that's because I'm expecting things to get kind of crazy. On paper, this feels like a game that the Lions have zero chance to win, but if I've learned one thing in my life about picking NFL games, it's that teams always seem to win when you think they have zero chance to win, especially when they're coached by a guy who's most famous quote involves biting kneecaps off. I have no idea what Dan Campbell eats at his house on Thanksgiving Day, but there's a 50% chance it's kneecaps. The big problem in this game for the Lions is that they have one of the worst defenses in the NFL this year and they'll be playing a Bills offense that has been one of the best. The Lions have given up the most yards per game and the most points per game and that's definitely not a good combination when the team you're playing ranks second in both points scored and yards per game. If this game had been played four weeks ago, I'd probably have picked the Bills by 30, but the Lions are suddenly one of the hottest teams in football. If you combine that with the fact that the Bills have been in a slight offensive rut, that's the recipe for a game that could go down to the wire. I told you we'd talk about recipes. The pick: Bills 30-27 over Lions ): https://www.cbssports.com/nfl/news/nfl-week-12-picks-patriots-shock-vikings-on-thanksgiving-cowboys-steamroll-giants-packers-upset-eagles/
Buffalo Bills vs. Detroit Lions predictions and keys to Thanksgiving Day game 2022 (Sal’s prediction: Buffalo Bills 34, Detroit Lions 23. I had the sense that Allen took a deep cleansing breath last week after getting his act together late in the first half and then going on to play a clean game. He needed that, and that might be what gets him back to being MVP-level Allen against Detroit. He really didn’t take advantage of the perfect dome conditions against the Browns, but that might happen this time around against a vulnerable Lions defense. The Lions have played well in winning three in a row and there’s no doubt they always play hard for coach Dan Campbell, a guy who has Red Bull rather than blood running through his veins. But the Bills are clearly the better team and while I think the Lions will score some points, they won’t be able to go point for point with Buffalo.): https://www.democratandchronicle.com/story/sports/football/nfl/bills/2022/11/22/bills-vs-lions-prediction-and-keys-to-thanksgiving-day-game/69667045007/
SN Bender (Buffalo Bills (-9) at Detroit Lions: Detroit has lost on Thanksgiving each of the last four years. The Lions tightened up against the run against the Giants last week, but Allen's mobility is going to be an issue for this defense. Devin Singletary and James Cook will get in on the action, and that will set up play-action for Buffalo's receivers. Detroit, however, continues to improve around an offense that features a few playmakers in D'Andre Swift and Amon-Ra St. Brown. Jared Goff will have a solid game too, but the pressure of keeping up with Buffalo in the second half will lead to a pair of turnovers. Von Miller chips in a pair of sacks. Buffalo will win, but they will fall to 1-4 ATS on the road. Pick: Bills 34, Lions 27): https://www.sportingnews.com/us/nfl/news/nfl-picks-predictions-week-12/w3rsyuyzjfqzc1bnyzmxekhn
Walter football (Week 12 NFL Pick: Bills 38, Lions 24): https://walterfootball.com/nflpicks2022_12early.php
Athlon Sports Buffalo vs. Detroit: Bills Make Return Trip to the Motor City for Thanksgiving Matchup Against Surging Lions (Prediction: Bills 27, Lions 24): https://athlonsports.com/.amp/nfl/thanksgiving-day-buffalo-bills-vs-detroit-lions-prediction-picks-2022
SN - Bills vs. Lions odds, prediction, betting tips for NFL Thanksgiving game (Bills vs. Lions prediction - The Lions' winning streak will end on Thanksgiving, as the Bills puts up 30-plus points for the third-straight week. Detroit will find the end zone a couple of times thanks to Willams and Swift, but Diggs and Davis will be too much for Detroit's defense. PREDICTION: Bills 33, Lions 21.): https://www.sportingnews.com/us/nfl/news/bills-lions-odds-prediction-betting-tips-nfl-week-12/vxml9mrfyucpfajaydtxyysr
CFN Buffalo Bills at Detroit Lions Prediction, Game Preview (Buffalo Bills at Detroit Lions Prediction, Line
Buffalo 34, Detroit 23): https://collegefootballnews.com/2022/11/buffalo-bills-at-detroit-lions-prediction-game-preview-lines-tv
CBS Prisco (Buffalo Bills (-9.5) at Detroit Lions: This has the makings of a game with a lot of offense. Both teams can score, but the Bills can really score. They will put up a big number here as Josh Allen wins a second straight game in Detroit after beating the Browns last week in the same building. The track is fast and the Bills can fly. The Lions won't keep up. Pick: Bills 40, Lions 23): https://www.cbssports.com/nfl/news/priscos-week-12-nfl-picks-cowboys-bills-blow-out-opponents-on-thanksgiving-titans-get-revenge-on-bengals/
CBS Benjamin (Prediction: Bills 30, Lions 23): https://www.cbssports.com/nfl/news/nfl-week-12-power-rankings-chiefs-have-that-super-bowl-look-again-lions-surging-vikings-fall/
Get ready for Thanksgiving Day football: Previewing all three NFL games, including picks and matchup keys (Moody's pick: Bills 31, Lions 20; Walder's pick: Bills 34, Lions 17): https://www.espn.com/nfl/story/_/id/35075774/nfl-thanksgiving-day-games-schedule-picks-odds-injuries-stats-fantasy-tips
CBS Sullivan (Bills at Lions, Thursday: The Lions have been rolling the past few weeks, but I just have a hard time betting against Josh Allen with this line under double figures. Yes, Detroit's defense has played better in its previous three games, but that was against the Packers, Bears and Giants. Buffalo's offense is a different animal entirely. Allen has historically played well on Thanksgiving as the Bills are 2-0 SU in both games and the QB registered a 100+ passer rating in each contest. While I believe Buffalo's offense can get into the 30s indoors at Ford Field, I don't see the Lions doing that in this setting. Specifically, I have my doubts because of the protection in front of Jared Goff. Detroit grades as the 24th-ranked pass-blocking team in the NFL this season, according to Pro Football Focus. Meanwhile, Buffalo is the third-best pass rush team in the league under the same grading system. Projected score: Bills 33, Lions 21): https://www.cbssports.com/nfl/news/nfl-week-12-odds-picks-cowboys-thrash-giants-on-thanksgiving-steelers-edge-out-colts-on-monday-night/
CBS Dajani (Bills (7-3) at Lions (4-6): Don't look now, but the Lions are on a three-game win streak! Just three teams have scored 30 or more points in five games this season, and this matchup features two of them. The third is the Kansas City Chiefs. The Lions statistically have the No. 6 offense in the NFL (366.6 yards per game), but the defense is the worst in the NFL. Sill, Jared Goff and Co. and are coming off of a surprising 31-18 beatdown of the Giants last week. The Lions have lost five straight Thanksgiving games, and are 5-16 on the holiday over the past 21 years. Unfortunately for them, it looks like six straight losses on Thanksgiving are coming Thursday. The Bills have won two straight Thanksgiving games -- including a 31-6 beatdown of the New Orleans Saints last year. Despite falling behind to the Cleveland Browns 10-3 in the second quarter last week, the Bills reeled off 25 unanswered points, and ended up defeating Cleveland by eight points. Interestingly enough, that game was played in Detroit as well due to a Buffalo snowstorm. Betting against the Lions on Thanksgiving feels sacrilegious, yet profitable. My heart is rooting for Dan Campbell's squad to pull off a monster upset, but I think this could be a get-right spot for the Super Bowl favorites after a weird three weeks. I'm going to lay the points with the favorites. I'll lean to the Under as well. Prediction: Bills (-9.5) 30-20 over Lions): https://www.cbssports.com/nfl/news/nfl-thanksgiving-best-bets-2022-top-plays-on-point-spread-totals-and-player-props-for-holiday-games/
Fox sports (Prediction: The Bills boast a truly elite defense, but I wonder if the Lions might keep this game close for longer than many expect. Ultimately, though, Buffalo pulls ahead, and the defense helps it hold the lead. Bills 31, Lions 25 –Henry McKenna): https://www.foxsports.com/stories/nfl/nfl-week-12-predictions-analysis-key-matchups-and-stats-for-every-game
NFL.com (Bills win 30-23: The Lions went into their Week 6 bye ranked dead last -- by a healthy margin -- in defensive efficiency (DVOA) through five games. In the five games since, they are 14th. Progress! The effort is there. Detroit can slow down a Buffalo team trying to simplify life for Josh Allen, and the Lions' offensive line can lean on the Bills enough to make this an entertaining game. That's all we ask for, Lions!): https://www.nfl.com/news/week-12-nfl-game-picks-2022-nfl-season
PFT’s NFL Week 12 2022 Picks (Bills (-9.5) at Lions - MDS’s take: The annual Detroit Thanksgiving bloodbath may not be quite as ugly for the home team this year, as the Lions are riding a three-game winning streak. But it’s awfully tough to imagine them beating the Bills. MDS’s pick: Bills 20, Lions 13. Florio’s take: The Lions will try to feast on kneecaps before turkey. If it was anyone but the Bills, that three-game winning streak would have a great chance of extending to four. Florio’s pick: Bills 27, Lions 20.): https://profootballtalk.nbcsports.com/2022/11/23/pfts-nfl-week-12-2022-picks/
AP Maaddi (Buffalo (minus 9 1/2) at Detroit: Josh Allen and the Bills face a different crowd in Detroit this week. The Lions have allowed 19 points per game during a three-game winning streak. BILLS, 30-22): https://pro32.ap.org/article/thanksgiving-slate-features-five-winning-football-teams
USA Today (All 6 pick the Bills to win by scores of 34-27, 41-33, 33-20, 30-24, 30-16, 27-17): https://www.usatoday.com/story/sports/nfl/2022/11/23/nfl-picks-week-12-spreads-locks-thanksgiving-cowboys-giants/10758468002/
Game Theory: Week 12 win probabilities and score projections for the '22 season (Bills win 31-21): https://www.nfl.com/videos/game-theory-week-12-win-probabilities-and-score-projections-for-the-22-season
Freep (All 4 pick the Bills to win by scores of 35-24, 28-24, 31-24, 27-23): https://www.freep.com/story/sports/nfl/lions/2022/11/23/detroit-lions-buffalo-bills-game-predictions/69675135007/
Buffalo Bills at Detroit Lions odds, picks and predictions (Prediction - Bills 31, Lions 17): https://sportsbookwire.usatoday.com/2022/11/23/buffalo-bills-at-detroit-lions-odds-picks-and-predictions/
Bills vs. Lions preview: Is Buffalo offense primed for explosive day? Our writers make their picks (Both pick the Bills to win by scores of 35-24, 38-20): https://www.syracuse.com/buffalo-bills/2022/11/bills-vs-lions-preview-is-buffalo-offense-primed-for-explosive-day-our-writers-make-their-picks.html
Buffalo News - How we see it: News reporters predict Bills vs. Lions on Thanksgiving Day (All 4 pick the Bills to win by scores of 38-20, 31-23, 37-23, 37-24): https://buffalonews.com/sports/bills/how-we-see-it-news-reporters-predict-bills-vs-lions-on-thanksgiving-day/article_13ce3b66-6ab9-11ed-8b67-37a376041d78.html
Buffalo Bills at Detroit Lions: Predictions, picks and odds for NFL Week 12 matchup (Lance Pugmire: Bills 33, Lions 21: Detroit’s rise has been fun and should prompt a shootout with Josh Allen and the Bills, who return to Ford Field for a back-to-back game following Buffalo’s snow-day triumph over the Cleveland Browns.): https://www.usatoday.com/story/sports/nfl/2022/11/24/buffalo-bills-detroit-lions-predictions-picks-odds-nfl-week-12/10759700002/
PFN Yarris (Bills vs. Lions Prediction: Bills 24, Lions 23): https://www.profootballnetwork.com/bills-vs-lions-prediction-odds-pick-how-to-watch-week-12-2022/
PFN (Predictions: Beasley: Bills 30, Lions 24; Miller: Bills 30, Lions 24; Robinson: Bills 33, Lions 20): https://www.profootballnetwork.com/nfl-picks-predictions-lock-upset-scores-week-12-2022/
Football Meteorology For 2022 NFL Week 12 (Buffalo Bills at Detroit Lions (+9.5): As a Lions fan, I’m grateful for the three-game winning streak the team has right now; it’s first since 2017. Alas, there won’t be any extra gravy on that tasty meat. With both starting guards out with injuries and center Frank Ragnow probably in need of a game off himself, the Lions are in real trouble against a very underappreciated Bills defensive front. And that doesn’t even start with the idea of playing Josh Allen and Stefon Diggs without top CB Jeff Okudah, who is also out. Bills 33, Lions 13): https://football.realgm.com/analysis/3516/Football-Meteorology-For-2022-NFL-Week-12
SI (4 pick the Bills to win. 1 picks the Lions to win): https://www.si.com/nfl/2022/11/24/nfl-week-12-staff-expert-picks
CFN (12 pick the Bills to win. 1 picks the Lions to win): https://collegefootballnews.com/2022/11/nfl-expert-picks-predictions-lines-week-12-2022
Athlon sports (All 4 pick the Bills to win): https://athlonsports.com/nfl/nfl-week-12-picks-predictions-2022
FTW (All 3 pick the Bills to win): https://ftw.usatoday.com/lists/straight-up-nfl-picks-week-12-patriots-vikings-bengals-titans
CBS (All 6 pick the Bills to win): https://www.cbssports.com/nfl/picks/experts/straight-up/12/
86 pick the Bills to win. 8 pick the Lions to win. Average Score Prediction (2025-1445/64): Bills 32 Lions 23.
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