SN Bender (Chicago Bears at Detroit Lions (-4.5): Chicago coach Ben Johnson – the Lions' offensive coordinator from 2022-24 – makes a quick return to Ford Field. The Lions need to turn up the pressure here on Caleb Williams, and they will at home. Look for Jahymr Gibbs and David Montgomery to bounce back, too. The Lions were 5-5 ATS at home last season. Pick: Lions 31, Bears 22): https://www.sportingnews.com/us/nfl/news/nfl-picks-predictions-week-2/0b7fa48b624d0d671c388691
SN Iyer (Bears at Lions (-4.5, 47.5 o/u): Ben Johnson takes his team on a short week to the team whose offense he used to coordinate. But Detroit's dismal disappointment in Green Bay will lead to familiar run-based production with Jahmyr Gibbs, opening up Jared Goff in the passing game. Aidan Hutchinson and the Lions' defense will answer by doing enough to keep Caleb Williams in check. Pick: Lions win 24-21 but fail to cover the spread): https://www.sportingnews.com/us/nfl/news/nfl-picks-predictions-against-spread-week-2/01be2ef47ff598aefecd8ec5
CBS Prisco (Chicago Bears at Detroit Lions (-5.5): The Bears are on the road off a short week against the Lions coming off a road loss. The Lions didn't look good in the loss to the Packers, but now they can get the offense going against a Bears defense that collapsed in the fourth quarter against the Vikings. The Lions win it. Pick: Lions 30, Bears 17): https://www.cbssports.com/nfl/news/priscos-week-2-nfl-picks-underdog-chiefs-eagles-aaron-rodgers-steelers/
AP Pro picks (Chicago at Detroit - Line: Lions minus 6. Ben Johnson returns to Detroit after the Bears (0-1) blew a fourth-quarter lead to spoil his head coaching debut. The Lions (0-1) missed their former offensive coordinator in a subpar opener. Their next loss matches their entire total from last season. Chicago has lost 11 of its last 12 games. The Lions are 1-4 ATS in their last five home games. LIONS: 29-20): https://apnews.com/article/pro-picks-2025-week-2-cbc9d737ebe4245ad8bc8580f95d145e
USA Today (All 6 pick the Lions to win by scores of 28-23, 20-17, 31-21, 27-23, 28-24, 23-20): https://www.usatoday.com/story/sports/nfl-picks/2025/09/11/nfl-week-2-picks-spread-predictions-locks-chiefs-eagles-super-bowl/86080513007/
CBS Sullivan (Chicago Bears at Detroit Lions - The Lions offense looked like it missed Ben Johnson in Week 1, and Johnson himself looked like he missed the Lions offense, particularly late in Chicago's second-half collapse against Minnesota. Coming into this matchup, the story will be Johnson taking on his former team, but I fear Caleb Williams could be the main storyline. The Bears quarterback struggled mightily during that collapse against the Vikings, shaking my preseason confidence in them as a surprise contender. In Week 1, Williams had an off-target throw rate of 22.9%, the highest among quarterbacks. That was on full display when he missed a wide-open D.J. Moore for what would've been a back-breaking touchdown. It doesn't matter what magic Johnson schemes up if Williams can't deliver the football where it needs to go. Projected score: Lions 30, Bears 20): https://www.cbssports.com/nfl/news/agents-take-2025-ultimate-53-man-roster-thats-the-best-team-money-can-buy/
PFT (Bears at Lions (-6): From 15-2 in the 2024 regular season to 0-2 between the 2024 postseason and Week 1. The Lions are experiencing the growing pains of a team that is learning how to be a winner. Florio’s pick: Lions 27, Bears 23. Simms’s pick: Lions 24, Bears 17.): https://www.nbcsports.com/nfl/profootballtalk/rumor-mill/news/pfts-week-2-2025-nfl-picks-florio-vs-simms
NFL.com.(Lions 28-21, Lions 26-21, Lions 29-21, Lions 31-13, Lions 28-17): https://www.nfl.com/news/nfl-picks-week-2-2025-nfl-season
Chicago Sun-Times (All 5 pick the Lions to win by scores of 27-21, 27-20, 26-24, 24-23, 27-17): https://chicago.suntimes.com/bears/2025/09/11/bears-lions-picks-predictions-odds-point-spread-nfl-win-loss-detroit-chicago-ben-johnson-dan-campbell
Key Matchups That Will Decide Five of the Biggest Week 2 NFL Games (Bears (0–1) at Lions (0–1): Spread: Detroit -4.5. Key matchup: Both passing games vs. opposing secondaries. Key stat: The Lions didn’t record a single pressure in Week 1. Date, Time, TV: 1 p.m. ET Sept. 14, FOX. Ben Johnson makes his return to Detroit on Sunday in a game both he and his former team need to win after divisional losses last week. The defining question of this game is which team will find its passing attack first? In Caleb Williams’s debut with Johnson on Monday Night Football, he began 10-of-10 with a series of short passes and one on-the-run missile to Rome Odunze. After that, Williams struggled with accuracy. In fact, Williams had a bad throw percentage of 25.7%, the highest mark of any quarterback in Week 1, despite having an average pocket time of 2.4 seconds, sixth-highest in football. Against Detroit, Williams might be able to hold the ball and get away with it if the Lions’ front four is held down as it was by Green Bay in the season opener. In a 27–13 defeat to the Packers, the Lions had zero sacks and two quarterback hits. The Packers were so effective up front that Detroit didn’t record a single pressure on Jordan Love. As for Jared Goff, he attempted 39 passes in Week 1 and only eight traveled more than 10 yards. His average depth of target was 4.2 yards per attempt, the lowest of all 32 starting quarterbacks. Meanwhile, the Bears did a nice job against Vikings QB J.J. McCarthy in his first NFL start, limiting him to 143 yards despite a poor fourth quarter. On the interior, the Lions are going with a new trio in rookie guard Tate Ratledge and second-year man Christian Mahogany, with Graham Glasgow replacing retired All-Pro center Frank Ragnow. Early returns were poor, as Detroit ran for 2.1 yards per carry and Goff was sacked four times. Williams and Goff have to find their mojo quickly or face a 0–2 hole. Verdict: Lions 24, Bears 19): https://www.si.com/nfl/key-matchups-biggest-week-two-nfl-games
Bears vs. Lions Final Score Prediction for NFL Week 2 (Lions Favored, But Do They Cover?) (Final Score Prediction: Lions 23, Bears 20): https://www.si.com/betting/bears-vs-lions-final-score-prediction-nfl-week-2-lions-favored-but-do-they-cover
Lions-Bears Week 2 score predictions from MLive’s beat writers (All 3 pick the Lions to win by scores of 24-17, 30-14, 31-17): https://www.mlive.com/lions/2025/09/lions-bears-week-2-score-predictions-from-mlives-beat-writers.html
Detroit News (All 4 pick the Lions to win by scores of 28-17, 31-20, 27-20, 30-20): https://www.detroitnews.com/story/sports/nfl/lions/2025/09/12/predictions-detroit-lions-vs-chicago-bears/86049598007/
Bears at Lions: Five things to watch as both seek first win; plus prediction (PREDICTION: Lions 27, Bears 24): https://lionslowdown.com/2025/09/14/bears-at-lions-five-things-to-watch-as-both-seek-first-win-plus-prediction/
Lions vs Bears: Last-minute thoughts and final score prediction (Final score prediction - The Bears hit some big plays, but the Lions offense--and defense--make more. Should be an exciting game in Ford Field. Lions 26, Bears 19.): https://lionswire.usatoday.com/story/sports/nfl/lions/2025/09/14/lions-vs-bears-last-minute-thoughts-matchups-final-score-prediction/86135149007/
SI All Lions (All 4 pick the Lions to win by scores of 33-20, 23-17, 27-17, 24-13): https://www.si.com/nfl/lions/news/predictions-bears-lions-week-two-2025
Lions vs. Bears 2025 Prediction, Odds, Picks - Sep 14 (Prediction: Lions 35 - Bears 12): https://www.foxsports.com/articles/nfl/lions-vs-bears-2025-prediction-odds-picks-sep-14
Bears at Lions odds, picks and predictions (Prediction - Lions 20, Bears 17): https://sportsbookwire.usatoday.com/story/sports/nfl/2025/09/14/bears-at-lions-odds-picks-and-predictions/86136506007/
670 staff predictions: Bears-Lions (8 pick the Lions to win by scores of 31-27, 24-17, 20-16, 30-24, 28-24, 31-21, 22-19, 26-22. 1 picks the Bears to win 24-20): https://www.audacy.com/670thescore/sports/chicago-bears/670-staff-predictions-bears-lions-2025-week-2
Lions vs. Bears preview | Week 2 (8 pick the Lions to win by scores of 27-20, 28-21, 24-14, 23-20, 23-20, 25-17, 25-20, 24-21. 2 pick the Bears to win by scores of 30-27, 26-25): https://www.detroitlions.com/video/lions-vs-bears-preview-week-2
Bears Wire (3 pick the Lions to win by scores of 24-17, 27-21, 34-20. 1 picks the Bears to win 31-24): https://bearswire.usatoday.com/story/sports/nfl/bears/2025/09/12/bears-lions-game-picks-predictions-week-2/86110153007/
Our guide to every Week 2 NFL game: Matchup previews, predictions, picks and nuggets (Maldonado's pick: Lions 26, Bears 23. Moody's pick: Lions 31, Bears 23. Walder's pick: Bears 24, Lions 20: https://www.espn.com/nfl/story/_/id/46215166/nfl-week-2-picks-predictions-schedule-fantasy-football-odds-injuries-stats-2025
CBS Dajani (Chicago Bears at Detroit Lions (-5.5) - Dajani (Bears +5.5): The Bears' fourth-quarter collapse vs. the Minnesota Vikings was definitely embarrassing, but the Lions' loss in Green Bay was just as bad. The 3.8 yards per play were the fewest Detroit has averaged since 2021, and Sunday snapped a streak of 15 games where the Lions had scored at least 20 points. I expect Ben Johnson will have something for his former team. While these are two different squads now, keep in mind that the Lions have failed to cover at home vs. the Bears in each of the last two years … Lions 20, Bears 17. Taranto (Bears +5.5): The biggest takeaway I had from the Lions' Week 1 performance was that all that they had built under Dan Campbell now seems fragile enough that it may not survive losing both of their coordinators to head coaching jobs over the offseason. If "Same Old Lions" is to make a roaring return, it's going to happen by virtue of Ben Johnson coming back to serve notice that he's going to haunt his former team now and into the future -- Especially since he knows full well what Campbell likes and will try to do against a team that had outplayed the Minnesota Vikings for three quarters on Monday night ... Bears 21, Lions 10): https://www.cbssports.com/nfl/news/agents-take-2025-ultimate-53-man-roster-thats-the-best-team-money-can-buy/
Non-Score Picks:
ESPN (11 pick the Lions to win): https://www.espn.com/nfl/picks
CBS (All 5 pick the Lions to win): https://www.cbssports.com/nfl/picks/experts/straight-up/2/
SI (7 pick the Lions to win. 1 picks the Bears to win): https://www.si.com/betting/nfl-straight-up-moneyline-picks-for-every-game-in-week-2
FTW (7 pick the Lions. 1 picks the Bears): https://ftw.usatoday.com/story/sports/nfl/2025/09/11/nfl-straight-up-picks-week-2-do-we-actually-trust-steelers-or-cowboys/86074645007/
88 pick the Lions to win. 8 pick the Bears to win. Average Predicted Score (1810-1373/69): Lions 26 Bears 20.
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