SN Bender (Detroit Lions (-7.5) at Indianapolis Colts: The Lions have defeated three AFC South teams by a combined total of 130-49, and Detroit is 2-1 ATS when favored by more than seven points. Anthony Richardson, who totaled 304 yards and three TDs against the Jets, is a different challenge for Detroit, and the Colts are 5-2 ATS as an underdog. Still, Detroit has allowed just 48.5 rushing yards per game the past two weeks. That will be a difference in this game. Pick: Lions 34, Colts 21): https://www.sportingnews.com/us/nfl/news/nfl-picks-predictions-week-12/63951eaba3c38a43ce0f0aef
CBS Breech (The pick: Lions 34-20 over Colts): https://www.cbssports.com/nfl/news/nfl-week-12-picks-49ers-stun-packers-rams-upset-eagles-ravens-edge-chargers-in-battle-of-harbaugh-brothers/
SN Iyer (Lions (-7.5, 50.5 o/u) at Colts
Sunday 1 p.m. ET, CBS. Don't count out Detroit from scoring more than 50 points for a record-tying third time at some point this season. The Colts' defense is bad enough vs. the strengths of the Lions (rushing attack, downfield passing shots) to think there's a chance for the Lions to get there in Indy. The Colts should be more game on offense with Anthony Richardson, but not enough Jonathan Taylor costs the hosts. Pick: Lions win 38-24 and cover the spread.): https://www.sportingnews.com/us/nfl/news/nfl-picks-predictions-against-spread-week-12-ravens-chargers/82470e826dce899d05885246
Walter football (Week 12 NFL Pick: Lions 26, Colts 23): https://walterfootball.com/nflpicks2024_12early.php
CBS Prisco (Detroit Lions (-7.5) at Indianapolis Colts: The Colts looked good winning on the road at the Jets last week, but this is a major step up in competition. The Lions offense is clicking again and should have success against the Colts defense. The question is whether Anthony Richardson can do it two weeks in a row. I will take the Lions in this one. Pick: Lions 30, Colts 17): https://www.cbssports.com/nfl/news/priscos-week-12-nfl-picks-rams-cool-off-red-hot-eagles-in-prime-time-broncos-survive-rival-raiders-on-road/
CBS Sullivan (Lions at Colts - We haven't been afraid of laying big numbers this season, especially when it comes to the Lions, so why stop now? Sure, Anthony Richardson looked much better in his return as a starter last week, but how much of that was due to playing a New York Jets team that has already quit on the season? I expect to see more of the version of Richardson from earlier this season, where he barely was able to complete half of his passes this week, especially when he's forced into a pass-first game script against a Lions team that loves to pour it on against inferior opponents. Detroit is 4-1 ATS on the road this season with an average margin of victory sitting at a league-best 12 points. Projected score: Lions 33, Colts 23): https://www.cbssports.com/nfl/news/nfl-week-12-odds-picks-packers-further-dash-49ers-playoff-hopes-chargers-win-harbaugh-bowl/
NFL.com Video Lions vs. Colts preview | Week 12 (All 10 pick the Lions to win by scores of 28-21, 21-17, 35-21, 30-21, 30-20, 21-20, 33-24, 33-19, 30-20, 30-28): https://www.nfl.com/videos/lions-vs-colts-preview-week-12
Pro Picks: The ‘Harbowl’ is the only matchup in Week 12 featuring two teams with winning records (Detroit (9-1) at Indianapolis (5-6) - Line: Lions minus 7 1/2. The high-powered Lions are steamrolling teams without letting up. They want the NFC’s No. 1 seed and Jared Goff has led the offense to 52 points twice in the past four games. Anthony Richardson is coming off his best game in his return to the starting lineup for the Colts. His mobility presents a challenge for Detroit, which is still trying to fill a major void on the defensive line without injured star Aidan Hutchinson. LIONS: 30-20): https://apnews.com/article/harbaugh-ravens-chargers-herbert-jackson-03bcc21743e5964668adee4c72fbe7b5
CBS Dajani (Lions 28-21 over Colts (+7.5)): https://www.cbssports.com/nfl/news/nfl-week-12-picks-odds-spread-best-bets-russell-wilson-wins-again-49ers-upset-packers/
PFT’s Week 12 NFL picks, Florio vs. Simms (Lions (-7.5) at Colts - The Lions keep on roaring. Florio: Lions, 42-20. Simms: Lions 30-20.): https://www.nbcsports.com/nfl/profootballtalk/rumor-mill/news/pfts-week-12-nfl-picks-florio-vs-simms
USA Today (All 4 pick the Lions to win by scores of 38-20, 35-29, 33-20, 34-20): https://www.usatoday.com/story/sports/nfl-picks/2024/11/21/nfl-week-12-picks-spread-predictions-locks-ravens-chargers-harbaugh/76459241007/
NFL.com Week 12 NFL picks: Steelers unanimously predicted to beat Browns; Ravens or Chargers in Harbowl? (Lions 28-24, Lions 31-22, Lions 30-21, Lions 31-21, Lions 28-20): https://www.nfl.com/news/week-12-nfl-picks-2024-nfl-season
Lions vs. Colts Final Score Prediction for NFL Week 12 (Impossible to Fade the Lions?) (Final Score Prediction: Lions 27, Colts 19): https://www.si.com/betting/lions-vs-colts-final-score-prediction-for-nfl-week-12-impossible-fade-the-lions
Our guide to every Week 12 NFL game: Matchup previews, predictions, picks and nuggets (Kahler's pick: Lions 40, Colts 24. Moody's pick: Lions 37, Colts 20. Walder's pick: Lions 30, Colts 21): https://www.espn.com/nfl/story/_/page/nflviewguide-42531064/nfl-week-12-picks-schedule-fantasy-football-odds-injuries-stats-2024
Detroit News (All 4 pick the Lions to win by scores of 31-17, 33-20, 28-20, 38-27): https://www.detroitnews.com/story/sports/nfl/lions/2024/11/22/predictions-detroit-lions-at-indianapolis-colts/76391775007/
Colts Wire Prediction and betting odds for Colts vs Lions in Week 12 (Indianapolis Colts vs Lions prediction, pick - Detroit is a well-oiled machine and the Colts, while coming off an encouraging win with Richardson at the helm, are still battling inconsistency on both sides of the ball. I just don’t see the Colts having the firepower, or at least not steadily enough, to come away with the win. Prediction: Lions 34 – Colts 24): https://coltswire.usatoday.com/2024/11/23/indianapolis-colts-lions-odds-picks-predictions-nfl-week-12/
Indy Star (All 3 pick the Lions to win by scores of 38-24, 37-24); https://www.indystar.com/story/sports/nfl/colts/2024/11/22/nfl-week-12-picks-predictions-detroit-lions-vs-indianapolis-colts/76481209007/
Fox sports 2024 NFL Week 12 Predictions, Betting Odds & TV Schedule (Prediction: Lions 30, Colts 18): https://www.foxsports.com/articles/nfl/2024-nfl-week-12-predictions-betting-odds-tv-schedule
Athlon sports All Lions (Both pick the Lions to win by scores of 31-13, 35-21): https://athlonsports.com/nfl/all-lions/detroit-lions-vs-indianapolis-colts-keys-to-watch-predictions-in-week-12-matchup
Sports book wire (Prediction - Lions 30, Colts 23): https://sportsbookwire.usatoday.com/2024/11/23/detroit-lions-at-indianapolis-colts-odds-picks-and-predictions/
Lions look to keep winning road record perfect as they face Colts (PREDICTION: Lions 42, Colts 17): https://lionslowdown.com/2024/11/23/lions-look-to-keep-winning-road-record-perfect-as-they-face-colts/
Freep (All 4 pick the Lions to win by scores of 31-17, 40-17, 37-14, 31-16): https://www.freep.com/story/sports/nfl/lions/2024/11/24/detroit-lions-picks-vs-indianapolis-colts-going-for-6th-road-victory/76506084007/
Lions vs. Colts: Last-minute thoughts and final score prediction (Final score prediction - I have a feeling the Colts are going to make this a tighter game than a lot of fans expect. They’re going to hit on some big plays that the Lions defense doesn’t typically give up. I also have a feeling the Lions offense will be able to hit one or two more of those big plays than the Colts can. Should be a fun game but perhaps a nerve-racking one. Lions 33, Colts 27): https://lionswire.usatoday.com/2024/11/24/lions-vs-colts-game-rpeview-last-minute-matchup-thoughts-final-score-prediction/
SI All Lions (All 4 pick the Lions to win by scores of 38-20, 42-17, 38-24, 31-17): https://www.si.com/nfl/lions/news/predictions-lions-colts-week-twelve
Horseshoe Huddle Roundtable: Colts vs. Lions | Predictions & Picks (4 pick the Lions to win by scores of 31-20, 34-31, 31-27, 35-23. 1 picks the Colts to win 32-31): https://www.si.com/nfl/colts/news/horseshoe-huddle-roundtable-colts-lions-predictions-picks
USA Today Detroit Lions at Indianapolis Colts: Predictions, picks and odds for NFL Week 12 game (3 pick the Lions to win by scores of 27-17, 28-18, 31-13. 1 picks the Colts to win 29-27): https://www.usatoday.com/story/sports/nfl/2024/11/20/detroit-lions-indianapolis-colts-picks-predictions-odds-week-12/76390449007/
Non-Score Predictions:
ESPN (11 pick the Lions to win): https://www.espn.com/nfl/picks
CBS (All 5 pick the Lions.): https://www.cbssports.com/nfl/picks/experts/straight-up/12/
SI (All 6 pick the Lions to win): https://www.si.com/nfl/2024-nfl-week-12-staff-expert-picks
FTW (All 6 pick the Lions): https://ftw.usatoday.com/2024/11/nfl-straight-up-picks-week-12-packers-49ers-patriots-dolphins
PFN (All 9 pick the Lions to win): https://www.profootballnetwork.com/nfl-picks-predictions-week-12-2024/
Athletic (All 7 pick the Lions to win): https://www.nytimes.com/athletic/5939088/2024/11/24/lions-colts-how-to-watch-odds-picks-betting/
105 Pick the Lions to win. 2 Picks the Colts to win. The Average Predicted Score is (2076-1345/64): Lions 32 Colts 21
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